Recombinant Histone H4 anticorps

N° du produit ABIN7543354

Cet anticorps anti-Histone H4 est un anticorps Lapin Chimeric détectant Histone H4 dans WB, ELISA et Crys. Adapté pour Humain.

Aperçu rapide pour Recombinant Histone H4 anticorps (ABIN7543354)

Antigène: Histone H4

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp Histone H4 est non-conjugé

Application: Western Blotting (WB), ELISA, Crystallization (Crys)

Clone: 1A9D7

Détail du produit anti-Histone H4 anticorps

Fonction: Anti-Histone H4 [1A9D7], Rabbit IgG, kappa

Specificité: The antibody specifically recognizes simultaneous acetylations at K5 and K8 of histone H4. Lysine acetylation of core histones is one of the major posttranslational modifications involved in the control of eukaryotic gene expression.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing mice with Histone H4 protein with site-specific acetylations at K5 and K8.

Isotype: IgG kappa

Information d'application

Indications d'application: The specificity of the original format of the antibody for histone H4 proteins containing di-acetylation of K5acK8ac was confirmed by ELISA analysis. The antibody detected the histone H4 proteins containing at least the di-acetylation of K5acK8ac western blot analysis. The crystal structure of the complex of di-acetylated histone H4 and 1A9D7 Fab fragment was determined (Handoko et al., 2018, PMID: 30080437).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Histone H4

Antigène: Histone H4

Sujet: H4K5acK8ac, Histone H4 protein,

UniProt: P62805